Manhattan Medical Office Space

View our Manhattan medical space listings, each commercial property is suited to Healthcare professionals both small and large in NYC. Each space below offers a full range of amenties and options those in the medical industry demand.

70 West 36th Street
Midtown South Medical Space for Lease

3,060 SF

Brand new Partial floor unit; surgical suite available for rent by Herald Square; This fifth floor unit features everything a healthcare professional may need including the space, furniture, and tools included; a rare find and excellent option for those looking to expand, establish, or move their current practice into a new professional environment without losing momentum.

425 Fifth Avenue
Bryant Park / Midtown South / Grand Central

4,200 SF


ADA Compliant Sixth Floor Medical Pre-Built Unit; this listed space contains 5 to 6 private offices / exams rooms, 2 large consultation rooms, 1 large secretarial area or nursing station, 2 single occupant restrooms, a kitchenette, additonally this unit features plenty of storage space and overall the whole office is contained within a corner position in the building; facing Fifth Avenue and 38th Street. Beyond the basic this office enjoys high quality materials in its construction / layout having been built in 2002 – showing little wear in superb condition today. The landlord today is offering flexible leasing term ranging from 5 to 10 years!

633 Third Avenue
Grand Central Pre-Built Furnished Medical Space

1,200 SF

Let us introduce 4 individual offices with stunning view of the city skyline at 633 Third Avenue; Each of four individual offices is design specifically for Mental Health Professionals providing sound proof walls, solid wood doors with sound seal frames for privacy + all furnished with brand new carpet and common wood floor.

992 Fifth Avenue
Ground Level Manhattan Medical Office Space

1,200 SF

Newly available medical offices across the street from the Metropolitan Museum of Art; this office features its own private entrance off the street. In addition this spaces features an outstanding build-out complete with stunning custom reception and patient seating area, polished hardwood floors, 2 furnished examination rooms, a private office, and a gorgeous consultation room. CALL FOR PRICE TODAY

110 East 40th Street
Three Grand Central Medical Suites


The Grand Park Building has availabe THREE medical suites; the property predominately hosts healthcare professionals and their respective practices. The first unit is ready for your buildout, the second is a pre-built suite within a dental office, and the last unit offers a professional a move-in ready medical office; view our photosd and floor plans we'd be glad to setup a tour! CALL FOR PRICE TODAY

Available Sizes: 750 to 1500 / 3087 / 2849 SF

140 West 58th Street
Midtown West Hell's Kitchen Medical Office Space

1,300 SF

Hell's Kitchen / Midtown West newly available commercial space has come to market offering 1,300 SF. of dedicated medical office space. This basement level office is situated on 58th Street between Avenue of the Americas and Seventh Avenue within a AAA Class white glove mixed-use building. The space can be configured into 4 to 5 exam rooms and is flexible enough for a myriad of healthcare requirements. This office can be leased with a term extending out 5 to 10 years and can be rented immediately - great options for those seeking a long term stay with a fast move-in. The space is accessible 24/7 and is manned by a part-time conceirge; entry to the unit is gained via elevator 1 flight down.

East 22nd Street
Manhattan Medical Office Space

985 SF Negotiable

This medical space has got its own private entrance from the street which is a valuable asset and a convenience for clients. Furthermore, the clients should appreciate the nice environment of this medical space. The space is made to respond to most of the needs of a medical suite and is in perfect conditions.

22nd Street
Flatiron Medical Office Space

2,000 SF Negotiable

This ground floor medical office space is in the beautiful Gramercy Park area on 22nd and 2nd Avenue. It is move-in ready with 3-4 spacious exam rooms and 2 consultation rooms. This medical space is available for sale or you can rent this medical property for $6,900 per month. The landlord is ready to negotiate all terms! This could be the perfect office for your practice in an amazing Manhattan location!

30s & 6th Avenue
Penn Station Medical Office Space

2,800 SF Divisible Negotiable

This is an entire floor for sale in a beautiful building in the mid 30s on 6th Avenue. The floor is 2,800 square feet and would be a great space to buy as an investment and rent it out. It would also suit well for a medical office. The space is on a high floor, so there are tremendous views and the location is superb! It is right in the center of the Herald Square transportation hub, so commuting is a breeze.

244 East 32nd Street
Kips Bay Medical Office Sublet

1,500 SF

The following Kips Bay area medical space is available for lease today. This AAA Class Pediatric office is within walking distance to NYU Hospital and Bellevue Hospital; a great advantage for those whose practice is complemented by referrals or require a local presence near a hospital.

Available Sizes: 1,500 SF office + 800 SF basement

32nd Street
Garmercy Medical Office Space

10,000 SF Divisible Negotiable

Prime Location Medical Building - Spaces is build CALL Stanley Piesh your medical office specialist. EVERY MEDICAL SPACE EVERY BUILDING 212-594-7354 Save Time and Avoid Frustration Utilize Prime Manhattan Realty to identify the perfect space at NO FEE.

Available Sizes: 10,000 SF / 5,000 SF

33rd Street
Garmercy Medical Office Space

10,000 SF Divisible Negotiable

This great office in the Midtown, Murray Hill area would make a perfect medical space for any growing practice. The location is excellent, right near the subway, and the surroundings are trendy and growing rapidly. The building is in great shape as well and there is up to 10,000 square feet available! The office has tremendous views of lower midtown, and the neighborhood is beautiful!

36th Street & 6th Avenue
Penn Station Medical Space

2,750 SF Divisible Negotiable

This is a great potential medical space in New York's premier lower midtown location. This trendy location is right near the Herald Square transportation hub and has easy access for all employees and clients! This space is 2,750 square feet and is in a truly one of a kind building. Both the area and building are great and it has just been reduced in price to $2,065,000!

40s & 6th Avenue
Times Square Medical Office

1,150 SF Divisible Negotiable

This office would be perfect for a Medical Office space based on its size and location as well. At 1,150 sq ft, this office would be great for a growing medical practice, and the current owner is willing to negotiate on the price! At a reasonable $950,000, the owner just lowered the price, and this affordable price will allow room to customize the office to fit your business' needs.

110 East 40th Street
The Grand Park Building Medical Office Condo

2,562 SF

A raw medical condo in the Grand Park Building is now available for Purchase. This unit was built for medical use - at the moment, this commercial condo requires a complete face-lift, creating a great opportunity for the right professional seeking a space in which to put their creative stamp upon. The condo is currently configured with a reception area, seven exam rooms, and a pantry.

40th Street & Madison Avenue
Grand Central Medical Space

1,800 SF Divisible Negotiable

This medical space at 40th Street and Madison Avenue has a great location in the midtown area. This 1,800 sq. ft. space offers well-lit windowed offices and treatment rooms. It has a newly renovated reception bay with private bathrooms. The medical office space is located in a magnificent modern building with a large lobby that will feel welcoming to patients and staff.

45th Street
Grand Central Medical Office Space

2,450 SF Negotiable

This is a property for sale in the mid 40s on 6th Avenue. With its great Grand Central location and proximity to 5th Avenue, this professional building is in a prime location for any type of growing business. It would be perfect for a Medical Office space based on its size and location as well. At 2,450 sq ft, this office would be great for a growing medical practice, and the current owner is willing to negotiate on the price!

55th Street
Midtown Medical Office Space

2,500 SF Divisible Negotiable

A class 24/7 doorman building. High ceilings, wood floors, and video intercom. Furniture available.Terrific hi floor views! Lanldord welcomes medical use. ADA compliant. Central Air condition. Two private bathrooms in the suite. Elevator opend directly to the space. Full floor indentity. Landlord will contribute to the buildout.

Available Sizes: 3,200 SF / 2,500 SF / 2,000 SF / 1,600 SF

57th Street
Midtown Medical Office Space

2,500 SF Divisible Negotiable

This is a great medical space available on 57th and Lexington. It has superb transportation access from the 4,5,6 subway lines that would benefit your practice by giving patients ample access to your office. There are 2,500 sq ft available in this class A office building and the landlord just reduced prices to around $50/sq ft.

58th Street
Midtown Medical Office Space

2,100 SF Negotiable

Here on 58th Street and 7th Avenue we have a ground floor space in a great location. There are 2,100 sq ft available, and this space would make a great medical clinic or wellness center! In the same building we have a few upper floor offices available too that would be great for medical offices!

60th - 90th Streets
Upper East Side Medical Offices For Sale

3,000 SF Negotiable

We have a number of properties for sale in the 60s to 90s on the Upper East Side of Manhattan. These office spaces are in professional buildings which are in a prime location for any type of growing practice. These commercial spaces are priced very affordably and will allow for room to customize the office to fit your business' needs.

East 1st Street
East Village Medical Office

4,250 SF Negotiable

Brand new Medical space (Community Facility Use) with Ground floor entrance. In very high end residential condominium building; sales prices above $1300 per sq.ft. Ready for occupancy in two months. Architecturally very appealing building facing south and park with plaza like feeling.

85th Street
Upper East Side Medical Office Space

1,800 SF Negotiable

Upper East Side Office (dental space, and medical offices) is available to Tenants only. Terms are negotiable to meet your desires. This office offers large open windows to provide natural light and sights of Manhattan, high ceilings with exposed columns allow for maximum space and clearance. The landlord will build to suite your medical office space needs.

Church Street
Financial District Medical Office Space

3,050 SF Negotiable

This is a great brand new ground floor medical space in the Financial District. It is located on busy Cortland Street and is in and ADA compliant building. There are 3,050 sq ft available comprised of 6 exam rooms, a reception area, and multiple private offices. There is central HVAC and the space is 100% move-in ready

St Marks Place
East Village Medical Office

12,500 SF Negotiable

This is a very interesting selection of several brand new medical suites in East Village. These medical offices have all been hand picked in nice and refined locations and as close as possible to hospitals. The selection includes spaces ranging from 530 rsq. ft to 1150 rsq. ft and costing between $2000 and $4450 per month. Therefore, it could correspond to different budgets or size requirements.

For further information about specific commercial spaces and buildings in Manhattan, call Prime Manhattan Realty at (212) 268-8043. We will find the perfect space for your needs at no fee to you! We will help to negotiate you an ideal purchase that will save you time and money.